วิจัย นวัตกรรม และผลงานเด่น

In vitro comparison of cerumenolytic efficacy: 2.5 % sodium bicarbonate versus 0.5 % sodium docusate based on cerumen weight gain

Abstract Objective: This study aimed to compare the cerumeno [...]

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Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics

Abstract Direct-infusion mass spectrometry (DI-MS) and mass [...]

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Disproportionately Increasing Incidence of Inflammatory Bowel Disease in Females and the Elderly: An Update Analysis from the Global Burden of Disease Study 2021

Abstract Objective: To update the global burden of Inflammat [...]

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Cold-pressed extraction of perilla seed oil enriched with alpha-linolenic acid mitigates tumour progression and restores gut microbial homeostasis in the AOM/DSS mice model of colitis-associated colorectal cancer

Abstract The present investigation explores into the influen [...]

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Metabolic and genetic risk factors associated with pre-diabetes and type 2 diabetes in Thai healthcare employees: A long-term study from the Siriraj Health (SIH) cohort study

Abstract The study of non-communicable diseases (NCDs) in a [...]

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Discovery of procyanidin condensed tannins of (-)-epicatechin from Kratom, Mitragyna speciosa, as virucidal agents against SARS-CoV-2

Abstract Kratom, Mitragyna speciosa, is one of the most popu [...]

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Development of cancer-associated fibroblasts-targeting polymeric nanoparticles loaded with 8-O-methylfusarubin for breast cancer treatment

Abstract Cancer-associated fibroblasts (CAFs) are abundant s [...]

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Immunogenicity of intraperitoneal and intranasal liposome adjuvanted VLP vaccines against SARS-CoV-2 infection

Abstract Humans get SARS-CoV-2 infection mainly through inha [...]

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Characterization of airborne microbial communities in northern Thailand: Impacts of smoke haze versus non-haze conditions

Abstract Data on airborne microorganisms, particularly in So [...]

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Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells

Abstract While prostaglandin E2 (PGE2) is produced in human [...]

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MSC secretome from amniotic fluid halts IL-1β and TNF-α inflammation via the ERK/MAPK pathway, promoting cartilage regeneration in OA in vitro

Abstract Osteoarthritis (OA) is a degenerative disease that [...]

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Investigating common mutations in ATP7B gene and the prevalence of Wilson’s disease in the Thai population using population-based genome-wide datasets

Abstract Wilson’s disease (WD) is a rare metabolic dis [...]

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Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues

Abstract Several X-linked genes escape from X chromosome ina [...]

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Comparative quantitative trait loci analysis framework reveals relationships between salt stress responsive phenotypes and pathways

Abstract Soil salinity is a complex abiotic stress that invo [...]

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Accurate Prediction of Ion Mobility Collision Cross-Section Using Ion’s Polarizability and Molecular Mass with Limited Data

Abstract The rotationally averaged collision cross-section ( [...]

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GLIMMERS: glioma molecular markers exploration using long-read sequencing

Abstract Summary The revised WHO guidelines for classifying [...]

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Is Exon Skipping a Viable Therapeutic Approach for Vascular Ehlers–Danlos Syndrome with Mutations in COL3A1 Exon 10 or 15?

Abstract Vascular Ehlers–Danlos syndrome or Ehlers–Danlos sy [...]

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CAIM: coverage-based analysis for identification of microbiome

Abstract Accurate taxonomic profiling of microbial taxa in a [...]

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Identification of RNF213 as a Potential Suppressor of Local Invasion in Intrahepatic Cholangiocarcinoma

Abstract Intrahepatic cholangiocarcinoma (ICC) is a lethal c [...]

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Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases

Abstract Alternative splicing contributes to complex traits, [...]

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Identification of Candidate Genes for Salt Tolerance at Seedling Stage in Rice Using QTL-Seq and Chromosome Segment Substitution Line-Derived Population

Abstract Rice is a staple food for more than half of the wor [...]

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Single-cell RNA sequencing reveals the expansion of circulating tissue-homing B cell subsets in secondary acute dengue viral infection

Abstract The roles of antibodies secreted by subsets of B ce [...]

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Quantifying fecal and plasma short-chain fatty acids in healthy Thai individuals

Abstract Short-chain fatty acids (SCFAs) are involved in imp [...]

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Measurement of very low-molecular weight metabolites by traveling wave ion mobility and its use in human urine samples

Abstract The collision cross-sections (CCS) measurement usin [...]

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Data processing solutions to render metabolomics more quantitative: case studies in food and clinical metabolomics using Metabox 2.0

Abstract The rotationally averaged collision cross-section ( [...]

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A Precision Therapy Approach for Retinitis Pigmentosa 11 Using Splice-Switching Antisense Oligonucleotides to Restore the Open Reading Frame of PRPF31

Abstract Retinitis pigmentosa 11 is an untreatable, dominant [...]

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Angiotensin II promotes erythroid proliferation in a three-stage erythroid culture system

Abstract At present, the numbers of cultured erythroid cells [...]

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วิจัย นวัตกรรม และผลงานเด่น ภาควิชาชีวเคมี คณะแพทยศาสตร์ศิริราชพยาบาล 3

วิจัย นวัตกรรม และผลงานเด่น ภาควิชาชีวเคมี คณะแพทยศาสตร์ศิริ [...]

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Transcriptomic screening of novel targets of sericin in human hepatocellular carcinoma cells

Abstract Sericin, a natural protein derived from Bombyx mori [...]

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Epigallocatechin Gallate Potentiates the Anticancer Effect of AFP-siRNA-Loaded Polymeric Nanoparticles on Hepatocellular Carcinoma Cells

Abstract Sericin, a natural protein derived from Bombyx mori [...]

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