{"id":5012,"date":"2025-12-19T11:28:56","date_gmt":"2025-12-19T04:28:56","guid":{"rendered":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/?p=5012"},"modified":"2026-03-30T15:04:40","modified_gmt":"2026-03-30T08:04:40","slug":"multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics","status":"publish","type":"post","link":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/","title":{"rendered":"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics"},"content":{"rendered":"<p>Pattipong Wisanpitayakorn, Narumol Jariyasopit, Kassaporn Duangkumpha, Jun Xian Goh, Martin E Palmer, Yongyut Sirivatanauksorn, <strong> Sakda Khoomrung<\/strong> <\/p>\n<h2 class=\"title\">Abstract<\/h2>\n<div id=\"eng-abstract\" class=\"abstract-content selected\">\n<div class=\"title\">\n<p>Direct-infusion mass spectrometry (DI-MS) and mass spectrometry imaging (MSI) are powerful techniques for lipidomics research. However, annotating isomeric and isobaric lipids with these methods is challenging due to the absence of chromatographic separation. Recently, cyclic ion mobility mass spectrometry (cIM-MS) has been proposed to overcome this limitation. However, fluctuations in room conditions can affect ion mobility multipass arrival times, potentially reducing annotation confidence. In this study, we developed a multipass arrival time correction method that proved effective across various dates, room temperatures, ion mobility settings, and laboratories using mixtures of reference standards. We observed slight variations in the linear correction lines between lipid and nonlipid molecules, underscoring the importance of choosing appropriate reference molecules. Based on these results, we demonstrated that an accurate multipass arrival time database can be constructed from corrected t0 and tp for interlaboratory use and can effectively identify isomeric lipids in MSI using only a single measurement. This approach significantly simplifies the identification process compared to determining multipass collision cross-section, which requires multiple measurements that are both sample- and time-intensive for MSI. Additionally, we validated our multipass drift time correction method in shotgun lipidomics analyses of human and mouse serum samples and observed no matrix effect for the analysis. Despite variations in dates, room temperatures, instruments, and ion mobility settings, our approach reduced the mean drift time differences from over 2% to below 0.2%.<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsmeasuresciau.4c00077\">https:\/\/pubs.acs.org\/doi\/10.1021\/acsmeasuresciau.4c00077<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Pattipong Wisanpitayakorn, Narumol Jariyasopit, Kassaporn Duangkumpha, Jun Xian Goh, Martin E Palmer, Yongyut Sirivatanauksorn, Sakda Khoomrung Abstract Direct-infusion mass spectrometry (DI-MS) and mass spectrometry imaging (MSI) are powerful techniques for lipidomics research. However, annotating isomeric and isobaric lipids with these methods is challenging due to the absence of chromatographic separation. Recently, cyclic ion mobility mass [&#8230;]\n","protected":false},"author":6,"featured_media":4624,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[],"class_list":["post-5012","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-innovation-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\" \/>\n<meta property=\"og:description\" content=\"Pattipong Wisanpitayakorn, Narumol Jariyasopit, Kassaporn Duangkumpha, Jun Xian Goh, Martin E Palmer, Yongyut Sirivatanauksorn, Sakda Khoomrung Abstract Direct-infusion mass spectrometry (DI-MS) and mass spectrometry imaging (MSI) are powerful techniques for lipidomics research. However, annotating isomeric and isobaric lipids with these methods is challenging due to the absence of chromatographic separation. Recently, cyclic ion mobility mass [...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/SIBBprogram\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-19T04:28:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-30T08:04:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2025\/12\/images_large_tg4c00077_0006.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"542\" \/>\n\t<meta property=\"og:image:height\" content=\"551\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Poorintra Sakuna\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Poorintra Sakuna\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/\"},\"author\":{\"name\":\"Poorintra Sakuna\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#\\\/schema\\\/person\\\/75170c4a414d080cfd0b7428b2e0d11a\"},\"headline\":\"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics\",\"datePublished\":\"2025-12-19T04:28:56+00:00\",\"dateModified\":\"2026-03-30T08:04:40+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/\"},\"wordCount\":265,\"publisher\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/images_large_tg4c00077_0006.jpeg\",\"articleSection\":[\"Research Innovation\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/\",\"name\":\"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/images_large_tg4c00077_0006.jpeg\",\"datePublished\":\"2025-12-19T04:28:56+00:00\",\"dateModified\":\"2026-03-30T08:04:40+00:00\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/images_large_tg4c00077_0006.jpeg\",\"contentUrl\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2025\\\/12\\\/images_large_tg4c00077_0006.jpeg\",\"width\":542,\"height\":551},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/\",\"name\":\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 Department of Biochemistry\",\"description\":\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25\",\"publisher\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#organization\",\"name\":\"Faculty of Medicine Siriraj Hospital, Mahidol University\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2023\\\/10\\\/logo-01.png\",\"contentUrl\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2023\\\/10\\\/logo-01.png\",\"width\":512,\"height\":512,\"caption\":\"Faculty of Medicine Siriraj Hospital, Mahidol University\"},\"image\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/SIBBprogram\\\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/#\\\/schema\\\/person\\\/75170c4a414d080cfd0b7428b2e0d11a\",\"name\":\"Poorintra Sakuna\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"caption\":\"Poorintra Sakuna\"},\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/en\\\/author\\\/sibc_poorintra\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/","og_locale":"en_US","og_type":"article","og_title":"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","og_description":"Pattipong Wisanpitayakorn, Narumol Jariyasopit, Kassaporn Duangkumpha, Jun Xian Goh, Martin E Palmer, Yongyut Sirivatanauksorn, Sakda Khoomrung Abstract Direct-infusion mass spectrometry (DI-MS) and mass spectrometry imaging (MSI) are powerful techniques for lipidomics research. However, annotating isomeric and isobaric lipids with these methods is challenging due to the absence of chromatographic separation. Recently, cyclic ion mobility mass [...]","og_url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/","og_site_name":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","article_publisher":"https:\/\/www.facebook.com\/SIBBprogram\/","article_published_time":"2025-12-19T04:28:56+00:00","article_modified_time":"2026-03-30T08:04:40+00:00","og_image":[{"width":542,"height":551,"url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2025\/12\/images_large_tg4c00077_0006.jpeg","type":"image\/jpeg"}],"author":"Poorintra Sakuna","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Poorintra Sakuna","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/#article","isPartOf":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/"},"author":{"name":"Poorintra Sakuna","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#\/schema\/person\/75170c4a414d080cfd0b7428b2e0d11a"},"headline":"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics","datePublished":"2025-12-19T04:28:56+00:00","dateModified":"2026-03-30T08:04:40+00:00","mainEntityOfPage":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/"},"wordCount":265,"publisher":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#organization"},"image":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/#primaryimage"},"thumbnailUrl":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2025\/12\/images_large_tg4c00077_0006.jpeg","articleSection":["Research Innovation"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/","name":"Multi-Pass Arrival Time Correction in Cyclic Ion Mobility Mass Spectrometry for Imaging and Shotgun Lipidomics - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","isPartOf":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/#primaryimage"},"image":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/#primaryimage"},"thumbnailUrl":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2025\/12\/images_large_tg4c00077_0006.jpeg","datePublished":"2025-12-19T04:28:56+00:00","dateModified":"2026-03-30T08:04:40+00:00","inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/multi-pass-arrival-time-correction-in-cyclic-ion-mobility-mass-spectrometry-for-imaging-and-shotgun-lipidomics\/#primaryimage","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2025\/12\/images_large_tg4c00077_0006.jpeg","contentUrl":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2025\/12\/images_large_tg4c00077_0006.jpeg","width":542,"height":551},{"@type":"WebSite","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#website","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/","name":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 Department of Biochemistry","description":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25","publisher":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#organization","name":"Faculty of Medicine Siriraj Hospital, Mahidol University","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2023\/10\/logo-01.png","contentUrl":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2023\/10\/logo-01.png","width":512,"height":512,"caption":"Faculty of Medicine Siriraj Hospital, Mahidol University"},"image":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/SIBBprogram\/"]},{"@type":"Person","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/#\/schema\/person\/75170c4a414d080cfd0b7428b2e0d11a","name":"Poorintra Sakuna","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","caption":"Poorintra Sakuna"},"url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/author\/sibc_poorintra\/"}]}},"_links":{"self":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/posts\/5012","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/comments?post=5012"}],"version-history":[{"count":4,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/posts\/5012\/revisions"}],"predecessor-version":[{"id":5658,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/posts\/5012\/revisions\/5658"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/media\/4624"}],"wp:attachment":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/media?parent=5012"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/categories?post=5012"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/en\/wp-json\/wp\/v2\/tags?post=5012"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}