{"id":6376,"date":"2026-08-28T10:00:43","date_gmt":"2026-08-28T03:00:43","guid":{"rendered":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/?p=6376"},"modified":"2026-08-28T10:03:54","modified_gmt":"2026-08-28T03:03:54","slug":"bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis"},"content":{"rendered":"<p>Nipith Charoenngam, Thanitsara Rittiphairoj, Ben Ponvilawan, Aunchalee Jaroenlapnopparat, Palapun Waitayangkoon, Pichatorn Suppakitjanusant, Vitchapong Prasitsumrit, Chatlert Pongchaiyakul, Michael F Holick<\/p>\n<h2 class=\"title\">Abstract<\/h2>\n<div id=\"eng-abstract\" class=\"abstract-content selected\">\n<div class=\"title\">\n<p><strong>Objective<\/strong>: To investigate bone fragility in patients with hereditary connective tissue disorders (HCTD), including Ehlers-Danlos syndrome (EDS), Marfan&#8217;s syndrome (MFS) and Loeys-Dietz syndrome (LDS).<\/p>\n<p><strong>Methods<\/strong>: From inception to June 2022, potentially eligible studies were identified in the Medline and EMBASE databases using search strategy that included terms for &#8220;HCTD&#8221;, &#8220;Fracture&#8221; and &#8220;Osteoporosis&#8221;. Eligible studies must consist of a group of patients with HCTD and report prevalence\/incidence of fracture\/osteoporosis in their participants, with or without comparison with healthy individuals. Point estimates with standard errors were obtained from each study and combined using the generic inverse variance method.<\/p>\n<p><strong>Results<\/strong>: Among the 4206 articles identified, 19 studies were included. The pooled prevalence of fracture in EDS, MFS, and LDS were 44% (95% confidence interval [CI], 25% to 65%, I2 88%), 17% (95% CI, 11% to 26%, I2 68%), 69% (95% CI, 47% to 85%, I2 83%), respectively. The pooled prevalence of osteoporosis in EDS was 17% (95% CI, 8% to 34%, I2 96%). EDS was associated with fracture [pooled odds ratio {OR} 4.90 (95% CI, 1.49 &#8211; 16.08, I2 86%)], but not osteoporosis [pooled OR 1.34 (95% CI, 0.28 &#8211; 6.36, I2 87%). One study reported a 5% (95% CI, 3% to 8%) prevalence of osteoporosis in MFS, which was associated with fracture [incidence rate ratio 1.35 (95% CI, 1.18 &#8211; 1.55)] and osteoporosis [subhazard ratio 3.97 (95% CI, 2.53 &#8211; 6.25)].<\/p>\n<p><strong>Conclusion<\/strong>: EDS was associated with fracture, which could be independent of osteoporosis status. MFS had a milder degree of increased risk of fracture and osteoporosis. Despite no data from cohort studies, there was a significantly higher rate of fracture in LDS.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36804968\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36804968\/<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Nipith Charoenngam, Thanitsara Rittiphairoj, Ben Ponvil [&#8230;]\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-6376","post","type-post","status-publish","format-standard","hentry","category-3"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/\" \/>\n<meta property=\"og:locale\" content=\"th_TH\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\" \/>\n<meta property=\"og:description\" content=\"Nipith Charoenngam, Thanitsara Rittiphairoj, Ben Ponvil [...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/SIBBprogram\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-08-28T03:00:43+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-08-28T03:03:54+00:00\" \/>\n<meta name=\"author\" content=\"Poorintra Sakuna\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Poorintra Sakuna\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 \u0e19\u0e32\u0e17\u0e35\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\\\/\"},\"author\":{\"name\":\"Poorintra Sakuna\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/person\\\/75170c4a414d080cfd0b7428b2e0d11a\"},\"headline\":\"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis\",\"datePublished\":\"2026-08-28T03:00:43+00:00\",\"dateModified\":\"2026-08-28T03:03:54+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\\\/\"},\"wordCount\":266,\"publisher\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#organization\"},\"articleSection\":[\"\u0e27\u0e34\u0e08\u0e31\u0e22 \u0e19\u0e27\u0e31\u0e15\u0e01\u0e23\u0e23\u0e21 \u0e41\u0e25\u0e30\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e40\u0e14\u0e48\u0e19\"],\"inLanguage\":\"th\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\\\/\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\\\/\",\"name\":\"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#website\"},\"datePublished\":\"2026-08-28T03:00:43+00:00\",\"dateModified\":\"2026-08-28T03:03:54+00:00\",\"inLanguage\":\"th\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\\\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#website\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/\",\"name\":\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 Department of Biochemistry\",\"description\":\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\",\"publisher\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"th\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#organization\",\"name\":\"Faculty of Medicine Siriraj Hospital, Mahidol University\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"th\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2023\\\/10\\\/logo-01.png\",\"contentUrl\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2023\\\/10\\\/logo-01.png\",\"width\":512,\"height\":512,\"caption\":\"Faculty of Medicine Siriraj Hospital, Mahidol University\"},\"image\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/SIBBprogram\\\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/person\\\/75170c4a414d080cfd0b7428b2e0d11a\",\"name\":\"Poorintra Sakuna\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"th\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"caption\":\"Poorintra Sakuna\"},\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/author\\\/sibc_poorintra\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/","og_locale":"th_TH","og_type":"article","og_title":"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","og_description":"Nipith Charoenngam, Thanitsara Rittiphairoj, Ben Ponvil [...]","og_url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/","og_site_name":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","article_publisher":"https:\/\/www.facebook.com\/SIBBprogram\/","article_published_time":"2026-08-28T03:00:43+00:00","article_modified_time":"2026-08-28T03:03:54+00:00","author":"Poorintra Sakuna","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Poorintra Sakuna","Est. reading time":"2 \u0e19\u0e32\u0e17\u0e35"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/#article","isPartOf":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/"},"author":{"name":"Poorintra Sakuna","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/person\/75170c4a414d080cfd0b7428b2e0d11a"},"headline":"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis","datePublished":"2026-08-28T03:00:43+00:00","dateModified":"2026-08-28T03:03:54+00:00","mainEntityOfPage":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/"},"wordCount":266,"publisher":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#organization"},"articleSection":["\u0e27\u0e34\u0e08\u0e31\u0e22 \u0e19\u0e27\u0e31\u0e15\u0e01\u0e23\u0e23\u0e21 \u0e41\u0e25\u0e30\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e40\u0e14\u0e48\u0e19"],"inLanguage":"th"},{"@type":"WebPage","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/","name":"Bone Fragility in Hereditary Connective Tissue Disorders: A Systematic Review and Meta-Analysis - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","isPartOf":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#website"},"datePublished":"2026-08-28T03:00:43+00:00","dateModified":"2026-08-28T03:03:54+00:00","inLanguage":"th","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/bone-fragility-in-hereditary-connective-tissue-disorders-a-systematic-review-and-meta-analysis\/"]}]},{"@type":"WebSite","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#website","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/","name":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 Department of Biochemistry","description":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","publisher":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"th"},{"@type":"Organization","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#organization","name":"Faculty of Medicine Siriraj Hospital, Mahidol University","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/","logo":{"@type":"ImageObject","inLanguage":"th","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/logo\/image\/","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2023\/10\/logo-01.png","contentUrl":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2023\/10\/logo-01.png","width":512,"height":512,"caption":"Faculty of Medicine Siriraj Hospital, Mahidol University"},"image":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/SIBBprogram\/"]},{"@type":"Person","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/person\/75170c4a414d080cfd0b7428b2e0d11a","name":"Poorintra Sakuna","image":{"@type":"ImageObject","inLanguage":"th","@id":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","caption":"Poorintra Sakuna"},"url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/author\/sibc_poorintra\/"}]}},"_links":{"self":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts\/6376","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/comments?post=6376"}],"version-history":[{"count":4,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts\/6376\/revisions"}],"predecessor-version":[{"id":6382,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts\/6376\/revisions\/6382"}],"wp:attachment":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/media?parent=6376"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/categories?post=6376"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/tags?post=6376"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}