{"id":6532,"date":"2026-09-07T10:54:07","date_gmt":"2026-09-07T03:54:07","guid":{"rendered":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/?p=6532"},"modified":"2026-09-07T10:56:52","modified_gmt":"2026-09-07T03:56:52","slug":"mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4","status":"publish","type":"post","link":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/","title":{"rendered":"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4"},"content":{"rendered":"

Tipparat Penglong, Apisara Saensuwanna, Husanai Jantapaso, Pongpon Phuwakanjana, Natee Jearawiriyapaisarn, Kittiphong Paiboonsukwong, Worrawit Wanichsuwan, Kanitta Srinoun<\/p>\n

Abstract<\/h2>\n
\n
\n

Oxidative damage to erythroid cells plays a key role in the pathogenesis of thalassemia. The oxidative stress in thalassemia is potentiated by heme, nonheme iron, and free iron produced by the Fenton reaction, due to degradation of the unstable hemoglobin and iron overload. In addition, the levels of antioxidant enzymes and molecules are significantly decreased in erythrocytes in \u03b1- and \u03b2-thalassemia. The control of oxidative stress in red blood cells (RBCs) is known to be mediated by microRNAs (miRNAs). In erythroid cells, microR-214 (miR-214) has been reported to respond to external oxidative stress. However, the molecular mechanisms underlying this phenomenon remain unclear, especially during thalassemic erythropoiesis. In the present study, to further understand how miR-214 aggravates oxidative stress in thalassemia erythroid cells, we investigated the molecular mechanism of miR-214 and its regulation of the oxidative status in thalassemia erythrocytes. We have reported a biphasic expression of miR-214 in \u03b2- and \u03b1-thalassemia. In the present study the effect of miR-214 expression was investigated by using miR -inhibitor and -mimic transfection in erythroid cell lines induced by hemin. Our study showed a biphasic expression of miR-214 in \u03b2- and \u03b1-thalassemia. Subsequently, we examined the effect of miR-214 on erythroid differentiation in thalassemia. Our study reveals the loss-of-function of miR-214 during translational activation of activating transcription factor 4 mRNA, leading to decreased reactive oxygen species levels and increased glutathione levels in thalassemia erythroid cell. Our results suggest that the expression of activating transcription factor 4 regulated by miR-214 is important for oxidative stress modulation in thalassemic erythroid cells. Our findings can help to better understand the molecular mechanism of miRNA and transcription factors in regulation of oxidative status in erythroid cells, particularly in thalassemia, and could be useful for managing and relieving severe anemia symptoms in patients in the future.<\/p>\n

https:\/\/murex.mahidol.ac.th\/en\/publications\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cell\/<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Tipparat Penglong, Apisara Saensuwanna, Husanai Jantapa […]\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-6532","post","type-post","status-publish","format-standard","hentry","category-3"],"yoast_head":"\nmiR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/\" \/>\n<meta property=\"og:locale\" content=\"th_TH\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\" \/>\n<meta property=\"og:description\" content=\"Tipparat Penglong, Apisara Saensuwanna, Husanai Jantapa [...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/SIBBprogram\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-09-07T03:54:07+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-07T03:56:52+00:00\" \/>\n<meta name=\"author\" content=\"Poorintra Sakuna\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Poorintra Sakuna\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 \u0e19\u0e32\u0e17\u0e35\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\\\/\"},\"author\":{\"name\":\"Poorintra Sakuna\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/person\\\/75170c4a414d080cfd0b7428b2e0d11a\"},\"headline\":\"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4\",\"datePublished\":\"2026-09-07T03:54:07+00:00\",\"dateModified\":\"2026-09-07T03:56:52+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\\\/\"},\"wordCount\":332,\"publisher\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#organization\"},\"articleSection\":[\"\u0e27\u0e34\u0e08\u0e31\u0e22 \u0e19\u0e27\u0e31\u0e15\u0e01\u0e23\u0e23\u0e21 \u0e41\u0e25\u0e30\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e40\u0e14\u0e48\u0e19\"],\"inLanguage\":\"th\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\\\/\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\\\/\",\"name\":\"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#website\"},\"datePublished\":\"2026-09-07T03:54:07+00:00\",\"dateModified\":\"2026-09-07T03:56:52+00:00\",\"inLanguage\":\"th\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\\\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#website\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/\",\"name\":\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 Department of Biochemistry\",\"description\":\"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\",\"publisher\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"th\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#organization\",\"name\":\"Faculty of Medicine Siriraj Hospital, Mahidol University\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"th\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2023\\\/10\\\/logo-01.png\",\"contentUrl\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/wp-content\\\/uploads\\\/2023\\\/10\\\/logo-01.png\",\"width\":512,\"height\":512,\"caption\":\"Faculty of Medicine Siriraj Hospital, Mahidol University\"},\"image\":{\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/SIBBprogram\\\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/#\\\/schema\\\/person\\\/75170c4a414d080cfd0b7428b2e0d11a\",\"name\":\"Poorintra Sakuna\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"th\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g\",\"caption\":\"Poorintra Sakuna\"},\"url\":\"https:\\\/\\\/www2.si.mahidol.ac.th\\\/department\\\/biochemistry\\\/author\\\/sibc_poorintra\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/","og_locale":"th_TH","og_type":"article","og_title":"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","og_description":"Tipparat Penglong, Apisara Saensuwanna, Husanai Jantapa [...]","og_url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/","og_site_name":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","article_publisher":"https:\/\/www.facebook.com\/SIBBprogram\/","article_published_time":"2026-09-07T03:54:07+00:00","article_modified_time":"2026-09-07T03:56:52+00:00","author":"Poorintra Sakuna","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Poorintra Sakuna","Est. reading time":"2 \u0e19\u0e32\u0e17\u0e35"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/#article","isPartOf":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/"},"author":{"name":"Poorintra Sakuna","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/person\/75170c4a414d080cfd0b7428b2e0d11a"},"headline":"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4","datePublished":"2026-09-07T03:54:07+00:00","dateModified":"2026-09-07T03:56:52+00:00","mainEntityOfPage":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/"},"wordCount":332,"publisher":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#organization"},"articleSection":["\u0e27\u0e34\u0e08\u0e31\u0e22 \u0e19\u0e27\u0e31\u0e15\u0e01\u0e23\u0e23\u0e21 \u0e41\u0e25\u0e30\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e40\u0e14\u0e48\u0e19"],"inLanguage":"th"},{"@type":"WebPage","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/","name":"miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","isPartOf":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#website"},"datePublished":"2026-09-07T03:54:07+00:00","dateModified":"2026-09-07T03:56:52+00:00","inLanguage":"th","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/mir-214-aggravates-oxidative-stress-in-thalassemic-erythroid-cells-by-targeting-atf4\/"]}]},{"@type":"WebSite","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#website","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/","name":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 Department of Biochemistry","description":"\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25","publisher":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"th"},{"@type":"Organization","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#organization","name":"Faculty of Medicine Siriraj Hospital, Mahidol University","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/","logo":{"@type":"ImageObject","inLanguage":"th","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/logo\/image\/","url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2023\/10\/logo-01.png","contentUrl":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-content\/uploads\/2023\/10\/logo-01.png","width":512,"height":512,"caption":"Faculty of Medicine Siriraj Hospital, Mahidol University"},"image":{"@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/SIBBprogram\/"]},{"@type":"Person","@id":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/#\/schema\/person\/75170c4a414d080cfd0b7428b2e0d11a","name":"Poorintra Sakuna","image":{"@type":"ImageObject","inLanguage":"th","@id":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c5e900607ffa8b31cad24dc9288ee1a1ee41e9efbb8d1c3094a7d7f3b5c2b78d?s=96&d=mm&r=g","caption":"Poorintra Sakuna"},"url":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/author\/sibc_poorintra\/"}]}},"_links":{"self":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts\/6532","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/comments?post=6532"}],"version-history":[{"count":4,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts\/6532\/revisions"}],"predecessor-version":[{"id":6536,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/posts\/6532\/revisions\/6536"}],"wp:attachment":[{"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/media?parent=6532"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/categories?post=6532"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www2.si.mahidol.ac.th\/department\/biochemistry\/wp-json\/wp\/v2\/tags?post=6532"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}