Assist.Prof.Dr.Wiwit Tantibhedhyangkul
Research Profile
My research focuses on host immune responses and diagnostic development for infectious and immunological diseases.
Current studies investigate B cell and innate immune responses to Mycobacterium abscessus, a major opportunistic pathogen in Thai immunodeficient patients with anti-interferon-gamma autoantibodies.
Research also explores host immune responses in tropical infectious diseases, particularly scrub typhus and leptospirosis, to better understand disease pathogenesis and immune regulation.
In parallel, I am involved in the development of diagnostic assays for scrub typhus, leptospirosis, and mycoplasma infections to improve early and accurate detection.
Another major area of interest is the development of immunological diagnostic tests for immunodeficiency diseases, aiming to enhance disease diagnosis, patient management, and translational applications in clinical immunology.
Publications
- Prachongsai I, Saisuwan R, Smosorn P, Kassaket N, Tantibhedhyangkul W. Interleukin-6 from Mycobacterium abscessus-infected macrophages enhances the survival of B cell-derived plasmablasts in vitro. Microbiol Spectr. 2026 Apr 20:e0252025. doi: 10.1128/spectrum.02520-25.
- Yamasmith E, Kinslow JD, Berg MG, Cloherty GA, Moy JN, Landay AL, Suputtamongkol Y, Tantibhedhyangkul W. Role of biomarkers in predicting disease severity in acute dengue and SARs-CoV-2-Infected patients. BMC Infect Dis. 2025 Dec 4;26(1):21. doi: 10.1186/s12879-025-12196-4.
- Tantibhedhyangkul W, Matamnan S, Longkunan A, Boonwong C, Khowawisetsut L. Endothelial Activation in Orientia tsutsugamushi Infection Is Mediated by Cytokine Secretion From Infected Monocytes. Front Cell Infect Microbiol. 2021 Jul 22;11:683017. doi: 10.3389/fcimb.2021.683017.
- Tantibhedhyangkul W, Wongsawat E, Matamnan S, Inthasin N, Sueasuay J, Suputtamongkol Y. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3):123. doi: 10.3390/antibiotics8030123.
- Tantibhedhyangkul W, Wongsawat E, Silpasakorn S, Waywa D, Saenyasiri N, Suesuay J, Thipmontree W, Suputtamongkol Y. Use of Multiplex Real-Time PCR To Diagnose Scrub Typhus. J Clin Microbiol. 2017 May;55(5):1377-1387. doi: 10.1128/JCM.02181-16. Epub 2017 Feb 15.
Curriculum Vitae
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