Keswadee Lapphra, MD

Biography

Dr. Keswadee Lapphra serves as an Associate Professor and Investigator in the Department of Pediatrics at the Faculty of Medicine Siriraj Hospital, Mahidol University, where she has been an Attending physician since 2005. Her early career included roles as a General Practitioner at Sawee Hospital and Prachubkirikhan Hospital, followed by a position as Pediatric staff in the Department of Tropical Pediatrics at the Faculty of Tropical Medicine, Mahidol University. Dr. Lapphra completed extensive specialized training, including a postdoctoral research fellowship at the Vaccine Evaluation Center of the University of British Columbia in Canada.

Education & Credentials

• M.D. – Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand (1994)
• Diploma, Thai Board of Pediatrics – Queen Sirikit National Institute of Child Health, Bangkok, Thailand (1997-2000)
• Fellowship in Pediatric Infectious Diseases – Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand (2002-2004)
• Certificate Fellowship in Pediatric Infectious Diseases – Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada (2008-2011)
• Postdoctoral Fellowship Research – Vaccine Evaluation Center, The Child & Family Research Institute, University of British Columbia, Vancouver, BC, Canada (2009-2011)

Research Interests

• Pediatric HIV and antiretroviral therapy outcomes and pharmacokinetics
• Vaccines, immunization efficacy, and adverse event tracking
• Tuberculosis in children, including diagnostics and drug-resistant strains
• Dengue virus infections and dengue vaccine evaluation

Selected Publications

• Optimizing Diagnostic Protocols for Pulmonary Tuberculosis in Children: A Comparison of Diagnostic Yields From One-day, Two-day and Three-day Specimen Collection Strategies. Pediatr Infect Dis J, 2025.
• Immunogenicity and safety of the live-attenuated tetravalent dengue vaccine (TAK-003) co-administered with recombinant 9-valent human papillomavirus vaccine. Vaccine, 2025.
• Re-emerging outbreaks of chikungunya virus infections of increased severity: A single-center, retrospective analysis of atypical manifestations in hospitalized children during the 2019 outbreak in Bangkok, Thailand. PLoS One, 2025.
• Effective and safe transfer of maternal antibodies persisting two months postpartum following maternal immunization with different doses of recombinant pertussis-containing vaccines. Vaccine, 2024.