คณะแพทยศาสตร์ศิริราชพยาบาล โดยศูนย์วิจัยเป็นเลิศด้านชีวโมเลกุลและฟีโนมศิริราช (SiMPC) ร่วมกับภาควิชาชีวเคมี เปิดศูนย์ SiMPC Service เพื่อให้บริการวิเคราะห์เมตาโบโลมิกส์และลิพิดส์โดมิกส์ด้วยเทคโนโลยี LC-MS/MS, GC-MS/MS และ Ion Mobility–Mass Spectrometry รองรับงานวิจัยทางคลินิก การวิเคราะห์ตัวอย่างอาหาร และผลิตภัณฑ์ธรรมชาติ เพื่อสนับสนุนการแพทย์แม่นยำและงานวิจัยด้านวิทยาศาสตร์สุขภาพ CONTACT US SiMPC Services Faculty of Medicine, Siriraj Hospital, Mahidol University, 9th floor, Sri Savarindira Building Service Manager: Puttandon Wongsomboon, PhD E-mail: puttandon.won@mahidol.ac.th Phone: 02-419-8735 Mobile: 082-280-6756
Author Archives: Poorintra Sakuna
Watsaphon Tangkullayanone, Nutchavadee Vorasan, Amphun Chaiboonchoe, Atthaphorn Trakarnsanga, Pariyada Tanjak, Thanawat Suwatthanarak, Woramin Riansuwan, Kullanist Thanormjit, Onchira Acharayothin, Asada Methasate, Yusuke Kinugasa, Bhoom Suktitipat, Vitoon Chinswangwatanakul Abstract Objective: To identify gene-expression features associated with lymph node metastasis (LNM) in colorectal cancer (CRC) and to develop a transcriptomic-clinical predictive model for preoperative nodal assessment. Materials and […]
Phanat Kittiphattanabawon, Hideki Kishimura, Soottawat Benjakul, Wonnop Visessanguan Abstract The yield and characteristics of collagen from Nile tilapia scale pretreated with ultrasound at 40 kHz for 2 h before pepsin-aided extraction for 12-72 h (US collagen) were investigated compared to collagen from the scales without ultrasonic pretreatment (non-US collagen). Both collagens’ yields increased with prolonged […]
Nithi Asavapanumas, Phaewa Chaiwijit, Ampa Suksatu, Saroj Kasemsinsup, Nongluk Saikachain, Juthamard Chantaraamporn, Suchanan Chieowisaman, Sarintip Nguantad, Damita Jevapatarakul, Narita Thungsatianpun, Tanapat Pornsukjantra, Tanida Chokpanuwat, Suwimon Manopwisedjaroen, Kanit Bhukhai, Patompon Wongtrakoongate, Suradej Hongeng, Ponpan Matangkasombut, Varodom Charoensawan, Arunee Thitithanyanont Abstract Neurological manifestations are common in COVID-19. However, a key limitation to understanding the mechanisms and developing […]
Tanva Thongkleang, Suyanee Thongchot, Kamonlatth Rodponthukwaji, Piriya Luangwattananun, Kwanruthai Tadpetch, Pa Thai Yenchitsomanus, Peti Thuwajit, Primana Punnakitikashem, Chanitra Thuwajit Abstract Triple-negative breast cancer (TNBC) is an aggressive malignancy with limited treatment options. It lacks hormone receptors and human epidermal growth factor receptor 2. The immunosuppressive tumor microenvironment (TME), particularly cancer-associated fibroblasts (CAFs), significantly hinders chimeric […]
Rathaporn Sumboonnanonda, Chodchanok Vijarnsorn, Puthita Saengpanit, Chatchawan Srisawat, Kwanjai Chotipanang, Sarawut Junnu, Supawan Kunnangja, Hathaichanok Rukprayoon, Phakkanan Phuangphan, Bordeesuda Suiwongsa, Sompong Liammongkolkul, Phakwan Laohathai, Narumon Densupsoontorn Abstract Background and Aims :Thiamin is a water-soluble vitamin essential for energy metabolism. Patients on long-term diuretics, particularly those with heart disease, are at risk of thiamin deficiency (TD) […]
Panintorn Thunwiriya, Tanaporn Phetruen, Phaewa Chaiwijit, Chaiyawat Tonawannakorn, Kanokwan Dekham, Nalumon Thadtapong, Soraya Chaturongakul, Varodom Charoensawan , Sittinan Chanarat, Danaya Pakotiprapha, Prut Hanutsaha Abstract Intravitreal injection anti-vascular endothelial growth factor (VEGF) drugs offer significant benefits for individuals with retinal diseases, yet high cost and limited availability impede widespread use. Compounding and repackaging present a potential […]
Rathachai Kaewlai, Jitti Chatpuwaphat, Sasima Tongsai, Piyachai Siriphiphatcharoen, Papasorn Wattanakul, Patcharaporn Thaisuriyo, Dhanawin Wongsaengchan, Napakadol Noppakunsomboon, Shanigarn Thiravit. Abstract Objectives: Appendicoliths are associated with failed nonoperative management in acute appendicitis and are used to exclude patients from this treatment. This study evaluated whether portovenous phase (PVP) and virtual noncontrast (VNC) images from rapid-kVP-switching dual-energy CT […]
Aunchalee Jaroenlapnopparat,Vitchapong Prasitsumrit, Ben Ponvilawan, Palapun Waitayangkoon , Nipith Charoenngam Abstract Background and aim: Clostridioides difficile infection (CDI) is a leading cause of nosocomial infection and is associated with both higher morbidity and mortality. Cirrhotic patients are more susceptible to CDI because of impaired gut immune response, use of proton pump inhibitor, and frequent hospitalization. […]
HashomMohd Hakim, Japareng Lalung, AungWin Tun, Patcharee Lertrit, Supannee Kaewsutthi, Citra Manela, Fika Tri Anggraini, Abd Rashid Nur Haslindawaty, Che Ghazali Norul Hajar, Hisham Atan Edinur Abstract The Kedayan is an indigenous population in Borneo who speak the Austronesian language, and majority of them live in Sabah and Sarawak on the Malaysian side of the […]

