Asst. Prof. Bhoom Suktitipat, MD, PhD

  • M.D. (First class honor), Faculty of Medicine Siriraj Hospital, Mahidol University
  • Ph.D. (Human Genetics/Genetic Epidemiology), Johns Hopkins University, MD, USA
  • Postdoctoral Visiting Fellow (Statistical Genetics), National Human Genome Research Institute, NIH, USA

Assistant Professor, Department of Biochemistry
Srisavarindhira Builid, Fl.10
Faculty of Medicine Siriraj Hospital
Mahidol University

Phone : (02) 419-9146

E-Mail : bhoom.suk@mahidol.ac.th

Website : https://goo.gl/uf6QdW

Selected Publications
1. Kaewsutthi, S., Phasukkijwatana, N., Joyjinda, Y., Chuenkongkaew, W., Kunhapan, B., Tun, A. W., Suktitipat, B., & Lertrit, P. (2011). Mitochondrial haplogroup background may influence Southeast Asian G11778A Leber hereditary optic neuropathy. Investigative ophthalmology & visual science, 52(7), 4742–4748. https://doi.org/10.1167/iovs.10-5816
2. Mathias, R. A., Sergeant, S., Ruczinski, I., Torgerson, D. G., Hugenschmidt, C. E., Kubala, M., Vaidya, D., Suktitipat, B., Ziegler, J. T., Ivester, P., Case, D., Yanek, L. R., Freedman, B. I., Rudock, M. E., Barnes, K. C., Langefeld, C. D., Becker, L. C., Bowden, D. W., Becker, D. M., & Chilton, F. H. (2011). The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans. BMC genetics, 12, 50. https://doi.org/10.1186/1471-2156-12-50
3. Suktitipat, B., Mathias, R. A., Vaidya, D., Yanek, L. R., Young, J. H., Becker, L. C., Becker, D. M., Wilson, A. F., & Fallin, M. D. (2012). The robustness of generalized estimating equations for association tests in extended family data. Human heredity, 74(1), 17–26. https://doi.org/10.1159/000341636
4. Kim, Y., Suktitipat, B., Yanek, L. R., Faraday, N., Wilson, A. F., Becker, D. M., Becker, L. C., & Mathias, R. A. (2013). Targeted deep resequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation. PloS one, 8(5), e64179. https://doi.org/10.1371/journal.pone.0064179
5. Suktitipat, B., Naktang, C., Mhuantong, W., Tularak, T., Artiwet, P., Pasomsap, E., Jongjaroenprasert, W., Fuchareon, S., Mahasirimongkol, S., Chantratita, W., Yimwadsana, B., Charoensawan, V., & Jinawath, N. (2014). Copy number variation in Thai population. PloS one, 9(8), e104355. https://doi.org/10.1371/journal.pone.0104355
6. Jirawatnotai, S., Sharma, S., Michowski, W., Suktitipat, B., Geng, Y., Quackenbush, J., Elias, J. E., Gygi, S. P., Wang, Y. E., & Sicinski, P. (2014). The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis. Cell cycle (Georgetown, Tex.), 13(18), 2889–2900. https://doi.org/10.4161/15384101.2014.946850
7. Tresukosol, D., Suktitipat, B., Hunnangkul, S., Kamkaew, R., Poldee, S., Tassaneetrithep, B., & Likidlilid, A. (2014). Effects of cytochrome P450 2C19 and paraoxonase 1 polymorphisms on antiplatelet response to clopidogrel therapy in patients with coronary artery disease. PloS one, 9(10), e110188. https://doi.org/10.1371/journal.pone.0110188
8. Li, Q., Kim, Y., Suktitipat, B., Hetmanski, J. B., Marazita, M. L., Duggal, P., Beaty, T. H., & Bailey-Wilson, J. E. (2015). Gene-Gene Interaction Among WNT Genes for Oral Cleft in Trios. Genetic epidemiology, 39(5), 385–394. https://doi.org/10.1002/gepi.21888
9. Qayyum, R., Becker, L. C., Becker, D. M., Faraday, N., Yanek, L. R., Leal, S. M., Shaw, C., Mathias, R., Suktitipat, B., & Bray, P. F. (2015). Genome-wide association study of platelet aggregation in African Americans. BMC genetics, 16, 58. https://doi.org/10.1186/s12863-015-0217-9
10. Pithukpakorn, M., Roothumnong, E., Angkasekwinai, N., Suktitipat, B., Assawamakin, A., Luangwedchakarn, V., Umrod, P., Thongnoppakhun, W., Foongladda, S., & Suputtamongkol, Y. (2015). HLA-DRB1 and HLA-DQB1 Are Associated with Adult-Onset Immunodeficiency with Acquired Anti-Interferon-Gamma Autoantibodies. PloS one, 10(5), e0128481. https://doi.org/10.1371/journal.pone.0128481
11. Qayyum, R., Becker, L. C., Becker, D. M., Faraday, N., Yanek, L. R., Leal, S. M., Shaw, C., Mathias, R., Suktitipat, B., & Bray, P. F. (2015). Genome-wide association study of platelet aggregation in African Americans. BMC genetics, 16, 58. https://doi.org/10.1186/s12863-015-0217-9
12. Suktitipat, B., Sathirareuangchai, S., Roothumnong, E., Thongnoppakhun, W., Wangkiratikant, P., Vorasan, N., Krittayaphong, R., Pithukpakorn, M., & Boonyapisit, W. (2017). Molecular investigation by whole exome sequencing revealed a high proportion of pathogenic variants among Thai victims of sudden unexpected death syndrome. PloS one, 12(7), e0180056. https://doi.org/10.1371/journal.pone.0180056
13. Lert-Itthiporn, W., Suktitipat, B., Grove, H., Sakuntabhai, A., Malasit, P., Tangthawornchaikul, N., Matsuda, F., & Suriyaphol, P. (2018). Validation of genotype imputation in Southeast Asian populations and the effect of single nucleotide polymorphism annotation on imputation outcome. BMC medical genetics, 19(1), 23. https://doi.org/10.1186/s12881-018-0534-8
14. Tirawanchai, N., Supapornhemin, S., Somkasetrin, A., Suktitipat, B., & Ampawong, S. (2018). Regulatory effect of Phikud Navakot extract on HMG-CoA reductase and LDL-R: potential and alternate agents for lowering blood cholesterol. BMC complementary and alternative medicine, 18(1), 258. https://doi.org/10.1186/s12906-018-2327-1
15. Ligthart, S., Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Macé, A., Sidore, C., Trompet, S., Mangino, M., … Alizadeh, B. Z. (2018). Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. American journal of human genetics, 103(5), 691–706. https://doi.org/10.1016/j.ajhg.2018.09.009
16. Bunbanjerdsuk, S., Vorasan, N., Saethang, T., Pongrujikorn, T., Pangpunyakulchai, D., Mongkonsiri, N., Arsa, L., Thokanit, N., Pongsapich, W., Anekpuritanang, T., Ngamphaiboon, N., Jinawath, A., Sunpaweravong, S., Pisitkun, T., Suktitipat, B., & Jinawath, N. (2019). Oncoproteomic and gene expression analyses identify prognostic biomarkers for second primary malignancy in patients with head and neck squamous cell carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 32(7), 943–956. https://doi.org/10.1038/s41379-019-0211-2
17. Niyomnaitham, S., Parinyanitikul, N., Roothumnong, E., Jinda, W., Samarnthai, N., Atikankul, T., Suktitipat, B., Thongnoppakhun, W., Limwongse, C., & Pithukpakorn, M. (2019). Tumor mutational profile of triple negative breast cancer patients in Thailand revealed distinctive genetic alteration in chromatin remodeling gene. PeerJ, 7, e6501. https://doi.org/10.7717/peerj.6501
18. Ngamphaiboon, N., Dechaphunkul, A., Setakornnukul, J., Dechaphunkul, T., Jiratrachu, R., Suktitipat, B., Jiarpinitnun, C., Pattaranutaporn, P., & Danchaivijitr, P. (2020). Optimal cumulative dose of cisplatin for concurrent chemoradiotherapy among patients with non-metastatic nasopharyngeal carcinoma: a multicenter analysis in Thailand. BMC cancer, 20(1), 518. https://doi.org/10.1186/s12885-020-07024-8
19. Thongpradit, S., Jinawath, N., Javed, A., Noojarern, S., Khongkraparn, A., Tim-Aroon, T., Lertsukprasert, K., Suktitipat, B., Jensen, L. T., & Wattanasirichaigoon, D. (2020). MITF variants cause nonsyndromic sensorineural hearing loss with autosomal recessive inheritance. Scientific reports, 10(1), 12712. https://doi.org/10.1038/s41598-020-69633-4
20. Rujirachun, P., Junyavoraluk, A., Pithukpakorn, M., Suktitipat, B., & Winijkul, A. (2020). Successful treatment of arrhythmia with β-blocker and flecainide combination in pregnant patients with Andersen-Tawil syndrome: A case report and literature review. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 26(3), e12798. https://doi.org/10.1111/anec.12798
21. Saengwimol, D., Chittavanich, P., Laosillapacharoen, N., Srimongkol, A., Chaitankar, V., Rojanaporn, D., Aroonroch, R., Suktitipat, B., Saisawang, C., Svasti, S., Hongeng, S., & Kaewkhaw, R. (2020). Silencing of the Long Noncoding RNA MYCNOS1 Suppresses Activity of MYCN-Amplified Retinoblastoma Without RB1 Mutation. Investigative ophthalmology & visual science, 61(14), 8. https://doi.org/10.1167/iovs.61.14.8
22. Tim-Aroon, T., Wichajarn, K., Katanyuwong, K., Tanpaiboon, P., Vatanavicharn, N., Sakpichaisakul, K., Kongkrapan, A., Eu-Ahsunthornwattana, J., Thongpradit, S., Moolsuwan, K., Satproedprai, N., Mahasirimongkol, S., Lerksuthirat, T., Suktitipat, B., Jinawath, N., & Wattanasirichaigoon, D. (2021). Infantile onset Sandhoff disease: clinical manifestation and a novel common mutation in Thai patients. BMC pediatrics, 21(1), 22. https://doi.org/10.1186/s12887-020-02481-3
23. Lertwilaiwittaya, P., Suktitipat, B., Khongthon, P., Pongsapich, W., Limwongse, C., & Pithukpakorn, M. (2021). Identification of novel mutation in RANKL by whole-exome sequencing in a Thai family with osteopetrosis; a case report and review of RANKL osteopetrosis. Molecular genetics & genomic medicine, 9(7), e1727. https://doi.org/10.1002/mgg3.1727
24. Jantaravinid, J., Jiamton, S., Srisawat, C., Suktitipat, B., & Tirawanchai, N. (2021). Expression Pattern of Genes in Condyloma Acuminata Treated with Clinacanthus nutans Lindau Cream versus Podophyllin. Evidence-based complementary and alternative medicine : eCAM, 2021, 5579520. https://doi.org/10.1155/2021/5579520
25. Tanjak, P., Suktitipat, B., Vorasan, N., Juengwiwattanakitti, P., Thiengtrong, B., Songjang, C., Therasakvichya, S., Laiteerapong, S., & Chinswangwatanakul, V. (2021). Risks and cancer associations of metachronous and synchronous multiple primary cancers: a 25-year retrospective study. BMC cancer, 21(1), 1045. https://doi.org/10.1186/s12885-021-08766-9
26. Dechaphunkul, T., Ngamphaiboon, N., Danchaivijitr, P., Jiratrachu, R., Geater, S. L., Pattaranutaporn, P., Jiarpinitnun, C., Setakornnukul, J., Suktitipat, B., & Dechaphunkul, A. (2022). Benefits of prophylactic percutaneous gastrostomy in patients with nasopharyngeal cancer receiving concurrent chemoradiotherapy: A multicenter analysis. American journal of otolaryngology, 43(2), 103356. https://doi.org/10.1016/j.amjoto.2021.103356
27. Toosaranont, J., Ruschadaariyachat, S., Mujchariyakul, W., Arora, J. K., Charoensawan, V., Suktitipat, B., Palmer, T. N., Fletcher, S., Wilton, S. D., & Mitrpant, C. (2022). Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts. International journal of molecular sciences, 23(7), 3937. https://doi.org/10.3390/ijms23073937
28. Veenin, K., Wattanasirichaigoon, D., Suktitipat, B., Noojarern, S., Lertrit, P., Tim-Aroon, T., Kaewsutthi, S., & Treepongkaruna, S. (2022). Association of Mitochondrial DNA Polymorphisms With Pediatric-Onset Cyclic Vomiting Syndrome. Frontiers in pediatrics, 10, 876436. https://doi.org/10.3389/fped.2022.876436
29. Chuenkongkaew, W. L., Chinkulkitnivat, B., Lertrit, P., Chirapapaisan, N., Kaewsutthi, S., Suktitipat, B., & Mitrpant, C. (2022). Clinical expression and mitochondrial deoxyribonucleic acid study in twins with 14484 Leber's hereditary optic neuropathy: A case report. World journal of clinical cases, 10(20), 6944–6953. https://doi.org/10.12998/wjcc.v10.i20.6944
30. Tanjak, P., Chaiboonchoe, A., Suwatthanarak, T., Acharayothin, O., Thanormjit, K., Chanthercrob, J., Suwatthanarak, T., Wannasuphaphol, B., Chumchuen, K., Suktitipat, B., Sampattavanich, S., Korphaisarn, K., Pongpaibul, A., Poungvarin, N., Grove, H., Riansuwan, W., Trakarnsanga, A., Methasate, A., Pithukpakorn, M., & Chinswangwatanakul, V.(2023). The KRAS-Mutant Consensus Molecular Subtype 3 Reveals an Immunosuppressive Tumor Microenvironment in Colorectal Cancer.Cancers, 15(4), 1098. https://doi.org/10.3390/cancers15041098
31. Dechaphunkul, A., Danchaivijitr, P., Jiratrachu, R., Dechaphunkul, T., Sookthon, C., Jiarpinitnun, C., Paoin, C., Setakornnukul, J., Suktitipat, B., Pattaranutaporn, P., & Ngamphaiboon, N. (2023). Real-world evidence of cisplatin versus carboplatin in patients with locally advanced nasopharyngeal carcinoma receiving concurrent chemoradiotherapy: A multicenter analysis. Asia-Pacific journal of clinical oncology, 19(1), 51–61. https://doi.org/10.1111/ajco.13668
32. Nirdnoy, N., Sranacharoenpong, K., Surawit, A., Pinsawas, B., Mongkolsucharitkul, P., Pongkunakorn, T., Manosan, T., Ophakas, S., Suta, S., Pumeiam, S., Mayurasakorn, K., & Siriraj Health Study Group. (2023). Validation of a Thai semiquantitative food frequency questionnaire (semi-FFQ) for people at risk of metabolic syndrome. Journal of health, population, and nutrition, 42(1), 13. https://doi.org/10.1186/s41043-023-00353-x
33. Suta, S., Surawit, A., Mongkolsucharitkul, P., Pinsawas, B., Manosan, T., Ophakas, S., Pongkunakorn, T., Pumeiam, S., Sranacharoenpong, K., Sutheeworapong, S., Poungsombat, P., Khoomrung, S., Akarasereenont, P., Thaipisuttikul, I., Suktitipat, B., & Mayurasakorn, K. (2023). Prolonged Egg Supplement Advances Growing Child's Growth and Gut Microbiota. Nutrients, 15(5), 1143. https://doi.org/10.3390/nu15051143
34. Wongsurawat, T., Jenjaroenpun, P., Anekwiang, P., Arigul, T., Thongrattana, W., Jamshidi-Parsian, A., Boysen, G., Suriyaphol, P., Suktitipat, B., Srirabheebhat, P., Cheunsuchon, P., Tanboon, J., Nookaew, I., & Sathornsumetee, S. (2023). Exploiting nanopore sequencing for characterization and grading of IDH-mutant gliomas. Brain pathology (Zurich, Switzerland), 34(1), e13203. https://doi.org/10.1111/bpa.13203
35. Hantaweepant, C., Suktitipat, B., Pithukpakorn, M., Chinthammitr, Y., Limwongse, C., Tansiri, N., Sawatnatee, S., Takpradit, C., Rotchanapanya, W., Pongudom, S., Charoenprasert, K., Paiboonsukwong, K., Thamprasert, W., Nolwachai, N., Rattanasawat, W., Sae-Aeng, B., Khorwanichakij, N., Saetow, P., Saengboon, S., Kamjornpreecha, K., … Siritanaratkul, N. (2023). Whole exome sequencing and rare variant association study to identify genetic modifiers, KLF1 mutations, and a novel double mutation in Thai patients with hemoglobin E/beta-thalassemia. Hematology (Amsterdam, Netherlands), 28(1), 2187155. https://doi.org/10.1080/16078454.2023.2187155
36. Thongrattana, W., Arigul, T., Suktitipat, B., Pithukpakorn, M., Sathornsumetee, S., Wongsurawat, T., & Jenjaroenpun, P. (2024). GLIMMERS: glioma molecular markers exploration using long-read sequencing. Bioinformatics advances, 4(1), vbae058. https://doi.org/10.1093/bioadv/vbae058
37. Chiablaem, K., Jinawath, A., Nuanpirom, J., Arora, J. K., Nasaree, S., Thanomchard, T., Singhto, N., Chittavanich, P., Suktitipat, B., Charoensawan, V., Chairoungdua, A., Jinn-Chyuan Sheu, J., Kiyotani, K., Svasti, J., Nakamura, Y., & Jinawath, N. (2024). Identification of RNF213 as a Potential Suppressor of Local Invasion in Intrahepatic Cholangiocarcinoma. Laboratory investigation; a journal of technical methods and pathology, 104(7), 102074. https://doi.org/10.1016/j.labinv.2024.102074
38. Mongkolsucharitkul, P., Surawit, A., Manosan, T., Ophakas, S., Suta, S., Pinsawas, B., Pongkunakorn, T., Pumeiam, S., Ratanasuwan, W., Homsanit, M., Charoencholvanich, K., Udomphorn, Y., Suktitipat, B., & Mayurasakorn, K. (2024). Metabolic and genetic risk factors associated with pre-diabetes and type 2 diabetes in Thai healthcare employees: A long-term study from the Siriraj Health (SIH) cohort study. PloS one, 19(6), e0303085. https://doi.org/10.1371/journal.pone.0303085
39. Own-Eium, P., Dejsuphong, D., Vathesatogkit, P., Sritara, P., Sura, T., Aekplakorn, W., Suktitipat, B., & Eu-Ahsunthornwattana, J. (2024). Investigating common mutations in ATP7B gene and the prevalence of Wilson's disease in the Thai population using population-based genome-wide datasets. Journal of human genetics, 70(1), 17–24. https://doi.org/10.1038/s10038-024-01292-z
40. Kamdee, K., Roothumnong, E., Thongnoppakhun, W., Korphaisarn, K., Nakthong, P., Dungort, P., Meesamarnpong, C., Wiboontanasarn, S., Tansa-Nga, W., Punuch, K., Pongsuktavorn, K., Tititumjariya, W., Lertbussarakam, C., Wattanarangsan, J., Sritun, J., Ridchuayrod, N., Pithukpakorn, M., & Suktitipat, B. (2025). Comprehensive germline and somatic profiling of high-risk Thai breast cancer via next-generation sequencing. Scientific reports, 15(1), 11427. https://doi.org/10.1038/s41598-025-95834-w
41. Kock, K. H., Tan, L. M., Han, K. Y., Ando, Y., Jevapatarakul, D., Chatterjee, A., Lin, Q. X. X., Buyamin, E. V., Sonthalia, R., Rajagopalan, D., Tomofuji, Y., Sankaran, S., Park, M. S., Abe, M., Chantaraamporn, J., Furukawa, S., Ghosh, S., Inoue, G., Kojima, M., Kouno, T., Lim J, Myouzen, K., Nguantad, S., Oh, JM., Rayan, NA., Sarkar, S., Suzuki, A., Thungsatianpun, N., Venkatesh, P.N., Moody, J., Nakano, M., Chen, Z., Tian, C., Zhang, Y., Tong, Y., Tan, C.T.Y., Tizazu, A.M., Loh, M., Hwang, Y.Y., Ho, RC., Larbi, A., Ng, T.P., Won, H.H., Wright, F.A., Villani, A.C., Park, J.E., Choi, M., Liu, B., Maitra, A., Pithukpakorn, M., Suktitipat, B., Ishigaki, K., Okada, Y., Yamamoto, K., Carninci, P., Chambers, J.C., Hon, C.C., Matangkasombut, P., Charoensawan, V., Majumder, P.P., Shin, J.W., Park, W.Y., Prabhakar, S. (2025). Asian diversity in human immune cells. Cell, 188(8), 2288–2306.e24. https://doi.org/10.1016/j.cell.2025.02.017