Professor emeritus Neelobol Neungton, MD, Dip Thai Brd Ped (Faculty Advisor)

  • M.D., Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand
  • Diplomate Thai Board of Pediatrics
  • Certified Thai Board of Family Medicine
  • Research Associate in Biological Chemistry, Washington University School of Medicine, St. Louis, U.S.A.

Office : 1011 Srisavarindira Bldg. 10th Fl. Department of Biochemistry. Faculty of Medicine, Siriraj Hospital, Bangkoknoi, Bangkok 10700

Laboratory : Srisavarindira Bldg. 9rd Fl.

Phone : (02)-419-8583 (office)
Fax: (02)-419-9141

E-Mail : neelobol.neu@mahidol.ac.th

Research Profile
  • Clinical biochemistry of diseases.
  • Porphyrias,
  • Alzheimer’s disease.
1. Rintoul, D. A., Neungton, N., & Silbert, D. F. (1982). Isolation and characterization of filipin-resistant LM cell variants not auxotrophic for sterol. Journal of lipid research, 23(3), 405–409.
2. Lau, C., Greenway, D. L., Freter, C. E., Neungton, N., Wattenberg, B., & Silbert, D. F. (1983). Conditions influencing formation of 16:0/16:0 molecular species in membrane phospholipids of Escherichia coli. The Journal of biological chemistry, 258(21), 13027–13033.
3. Chuntapet, P., Kalpravidh, R. W., Neungton, N.,, Mungkornkarn, C., & Skulchan, V. (1990). The determination of beta-aminoisobutyric acid in urine of normal and cancer patients. Southeast Asian Journal of Tropical Medicine and Public Health, 21(1), 1–6. Retrieved from https://pesquisa.bvsalud.org/portal/resource/pt/sea-138160.
4. Neungton, N.,Moongkarndi, P., Laohathai, K., Neungton, S., & Juntrachotiwit, P. (1992). Immuno-histological characterization of OVS1 and OVS2 monoclonal antibodies recognizing human ovarian mucinous cystadenocarcinoma. Asian Pacific journal of allergy and immunology, 10(2), 129–134.
5. Neungton, N.,Chearskul, S., Neungton, S., Srisawat, C., Angpitakpan, D., Sothanayongkul, R., et al. (1993). Evaluation of new ovarian cancer markers, STN, CA 546 and CA 72-4 in Thai patients. Siriraj Hospital Gazette, 45, 307–314.
6. Neungton, N., Kachintorn, U., Chinapak, O., Ong-Ajyooth, S., & Umpornsirirat, S. (1994). Significance of ascitic fluid white blood cells, pH, lactate, and other chemistry in immediate diagnosis of spontaneous bacterial peritonitis. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 77(5), 266–270.
7. Srisawat, C., Neungton, N., & Soiampornkul, R. (1995). Establishment of OVS3 monoclonal antibody recognizing human ovarian cancer. Siriraj Hospital Gazette, 47, 909–915.
8. Neungton, N., Moongkarndi, P., Neungton, S., Laohathai, K., Srisawat, C., Wachirutmanggur, L., & Thielfoldt, R. (1995). Establishment of OVS1 and OVS2 monoclonal antibodies recognizing human ovarian mucinous cystadenocarcinoma.Asian Pacific journal of allergy and immunology, 13(1), 47–53.
9. Dumrongdej, P., Lertrit, P., Wongmanee, U., Panichkul, N., & Neungton, N. (1998). Serum ceruloplasmin in Wilson's disease. Siriraj Hospital Gazette, 50, 576–581.
10. Boonvisudhi, K., Junnu, S., Soiampornkul, R., Supavilai, R., Wongmanee, U., Panichkul, N., & Neungton, N.(1999). Comparative analysis of venous blood lactate levels by automatic lactate strip kit (Accusport) and by standard Marbach's enzymatic method. Siriraj Hospital Gazette, 51, 791–800.
11. Permpikul, C., Ratanarat, R., & Neungton, N. (2000). Blood lactate determined by a portable device in critically ill patients. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 83(11), 1348–1353.
12. Neungton, N., Neungton, S., Leelaphatanadit, C., Dangrat, C., & Soiampornkul, R. (2002). p53 tumor suppressor gene mutation in ovarian cancer in Thai patients. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 85(6), 658–667.
13. Moongkarndi, P., Kaslungka, S., Kosem, N., Junnu, S., Jongsomboonkusol, S., Theptaranon, Y., & Neungton, N. (2003). Cytotoxicity and apoptosis of ovarian and breast cancer cell lines induced by OVS1 monoclonal antibody and paclitaxel. Asian Pacific journal of allergy and immunology, 21(1), 31–41.
14. Srisawat, C., Sanpakit, K., Wisutsareevong, W., Leenutaphong, V., Permpikul, C., & Neungton, N. (2004). A Girl with A Glowing Tooth : A Case of Congenital Erythropoietic Porphyria. Siriraj Medical Journal, 56(1), 26–32. retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245484
15. Moongkarndi, P., Kosem, N., Kaslungka, S., Luanratana, O., Pongpan, N., & Neungton, N. (2004). Antiproliferation, antioxidation and induction of apoptosis by Garcinia mangostana (mangosteen) on SKBR3 human breast cancer cell line. Journal of Ethnopharmacology, 90(1), 161–166. https://doi.org/10.1016/j.jep.2003.09.048
16. Junnu, S., Srisawat, C., Jantarapassvorn, S., Soi-ampornkul, R., Wattanaraksakul, N., & Neungton, N. (2005). Comparative Study of Two Screening Tests for Urinary Porphyrins in the Diagnosis of Porphyrias. Siriraj Medical Journal, 57(12), 531–536. retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245642
17. Soi-ampornkul, R., Junnu, S., Chotinaiwattarakul, W., Wongmanee, U., Suktitipat, B., &Neungton, N. (2006). Comparative Analysis of Serum Ceruloplasmin Levels in Wilson Disease by Conventional Enzymatic Assay and Immunologic Method. Siriraj Medical Journal, 58(1), 600–605. retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245669
18. Suwantarat, N., Srisawat, . C., Masaratana, P., Soi-ampornkul, R., Junnu, S., Roubsanthisuk, W. , & Neungton, N.(2006). Microalbuminuria Analysis in Thai Patients with Diabetes and Hypertension Using Albumin Blue 580 Fluorescence Assay. Siriraj Medical Journal, 58(10), 1050–1053. retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245940
19. Peerapittayamongkol, C., Srisawat, C., Junnu, S., Kanyok, S., Soiampornkul, R., Poonsawas, I., & Neungton, N. (2007). Porphyrias diagnosed types by HPLC analysis: 10 years Siriraj experience. Siriraj Medical Journal, 59, 356–360.
20. Chularojanamontri, L., Tuchinda, C., Srisawat,Neungton, N., Junnu, S., & Kanyok, S. (2008). Utility of plasma fluorometric emission scanning for diagnosis of the first 2 cases reports of variegate porphyria: a very rare type of porphyrias in Thai. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 91(12), 1915–1919.
21. Moongkarndi, P., Srisawat, C., Saetun, P., Jantaravinid, J., Peerapittayamongkol, C., Soi-ampornkul, R., Junnu, S., Sinchaikul, S., Chen, S. T., Charoensilp, P., Thongboonkerd, V., & Neungton, N. (2010). Protective effect of mangosteen extract against beta-amyloid-induced cytotoxicity, oxidative stress and altered proteome in SK-N-SH cells. Journal of proteome research, 9(5), 2076–2086. https://doi.org/10.1021/pr100049v
22. Sattayasai, J., Chaonapan, P., Arkaravichie, T., Soi-Ampornkul, R., Junnu, S., Charoensilp, P., Samer, J., Jantaravinid, J., Masaratana, P., Suktitipat, B., Manissorn, J., Thongboonkerd, V., Neungton, N., & Moongkarndi, P. (2013). Protective effects of mangosteen extract on H2O2-induced cytotoxicity in SK-N-SH cells and scopolamine-induced memory impairment in mice. PloS one, 8(12), e85053. https://doi.org/10.1371/journal.pone.0085053
23. Srisawat, C., Junnu, S., Peerapittayamongkol, C., Futrakul, A., Soi-ampornkul, R., Senanarong, V., Praditsuwan, R., Assantachai, P., & Neungton, N. (2013). The platelet amyloid precursor protein ratio as a diagnostic marker for Alzheimer's disease in Thai patients. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 20(5), 644–648. https://doi.org/10.1016/j.jocn.2012.06.008
24. Suthammarak, W., Numpraphrut, P., Charoensakdi, R.,Neungton, N., Tunrungruangtavee, V., Jaisupa, N., Charoensak, S., Moongkarndi, P., & Muangpaisan, W. (2016). Antioxidant-Enhancing Property of the Polar Fraction of Mangosteen Pericarp Extract and Evaluation of Its Safety in Humans. Oxidative medicine and cellular longevity, 2016, 1293036. https://doi.org/10.1155/2016/1293036
25. Muangpaisan, W., Wiputhanuphongs, P., Jaisupa, N., Junnu, S., Samer, J., Moongkarndi, P., Supapueng, O., Chalermsri, C., & Neungton, N. (2022). Effects of water-soluble mangosteen extract on cognitive function and neuropsychiatric symptoms in patients with mild to moderate Alzheimer's disease (WECAN-AD): A randomized controlled trial. Alzheimer's & dementia (New York, N. Y.), 8(1), e12292. https://doi.org/10.1002/trc2.12292

1.

Moongkarndi P, Srisawat C, Saetun P, Jantaravinid J, Peerapittayamonkol C, Soi-ampornkul R, Junnu S, Sinchaikul S, Chen ST, Charoensilp P, Thongboonkerd V, Neungton N. Protective effect of mangosteen extract against beta-amyloid-induced cytotoxicity, oxidative stress and altered proteome in SK-N-SH cells. มหกรรมสมุนไพรแห่งชาติครั้งที่ 8, 31 สิงหาคม – 4 กันยายน 2554, อิมแพค เมืองทองธานี นนทบุรี.

2.

Moongkarndi P, Srisawat C, Saetun P, Jantaravinid J, Peerapittayamonkol C, Soi-ampornkul R, Junnu S, Sinchaikul S, Chen ST, Charoensilp P, Thongboonkerd V, Neungton N. Protective effect of mangosteen extract against beta-amyloid-induced cytotoxicity, oxidative stress and altered proteome in SK-N-SH cells. Joint Conference in Medical Sciences 2011: Chula-Rama-Siriraj (JCMS2011), June 15-17, 2011 at IMPACT Exhibition and Convention Center, Thailand: 18.

3.

Moongkarndi P, Kosem N, Jongsomboonkusol S, Montririttigri K, Choljararux I, Samer J, Pattanapanyasat K, Neungton N. Herbal/natural health products for cancer care : turning medicinal plants into anticancer drugs. Oral presentation at 10th National Cancer Conference : A joint Meeting, November 2-4, 2009 at Miracle Grand Convention Hotel, Bangkok, Thailand.

4.

Neungton N, Moongkarndi P, Srisawat C, Jantaravinid J, Peerapittayamongkol C, Soiampornkul R, et al. Protective effect of mangosteen extract against beta-amyloid-induced apoptosis in SK-N-SH cells. Proceedings of the International Conference on Alzheimer’s Disease, July 11-16, 2009 at Vienna, Austria. Alzheimer’s&dementia J 2009;5:413-4.

5.

Jantaravinid J, Srisawat C, Moongkarndi P, Neungton N. Protective effect of mangosteen extract against oxidative stress induced by beta-amyloid in SK-N-SH cells. Proceedings of the 12th National Graduate Research Conference by Dean of Graduate Schools of Public University (DGPU) and Khon Kaen University, February 12-13, 2009 at Faculty of Engineering, Khon Kaen University, Khon Kaen, Thailand.

6.

Jantaravinid J, Srisawat C, Moongkarndi P, Neungton N. Protective effect of mangosteen extract against oxidative stress induced by beta-amyloid in SK-N-SH cells. Joint Conference in Medical Sciences. 2009:118.

7.

Neungton N, Srisawat C, Junnu S, Peerapittayamongkol C, Fitrakul A, Soiampornkul R, et al. Platelet amyloid precursor protien ratio as a diagmostic marker for Alzheimer’s Disease in Thai patients. A preliminary report [Abstract]. Presented in The 10th International Conference on Alzheimer’s Disease and related Disorder July 15-20, 2006 at IFEMA exhibition center Madrid, Spain. Alzheimer’s&dementia J; supplement; 2006;2:398.