Dr.Nathachit Limjunyawong
Research Profile
His current research focuses on understanding how environmental exposures influence immune-related diseases and lung cancer development.
His research encompasses two major areas. First, he investigates the immunological mechanisms underlying allergic and infectious diseases, with a particular focus on epithelial barrier function and innate immune responses involving granulocytes such as mast cells, eosinophils, and neutrophils.
Using multidisciplinary approaches, he examines how immune cells respond to diverse environmental stimuli and applies this knowledge to address regional health challenges, including parasitic infections such as Angiostrongylus-induced eosinophilic meningitis, allergic diseases caused by dust mite and cockroach, mechanisms of itch, and the health effects of PM2.5 air pollution. Second, his research explores the environmental and cellular mechanisms driving lung cancer carcinogenesis.
To support this work, his team is establishing a biobank of donor-matched normal lung and lung cancer o—a population disproportionately affected in Asia—and facilitating the development of population-specific prevention and therapeutic strategies.
Publications
- Charoennitiwat V, Sukwattananipaat P, Ratnarathorn N, Pewla-Oo S, Viriyautsahakul S, Thongsom C, et al. Comparative neuropathogenesis of Angiostrongylus cantonensis and Angiostrongylus malaysiensis infection in an experimental BALB/c mouse model. Acta Trop. 2026;279:108113.
- Kothari R, Abdulrahim MW, Oh HJ, Capuzzi DH, Kilgore CB, Nair SK, et al. A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis. Cell. 2025;188(20):5499–515 e20.
- Chien DC, Limjunyawong N, Cao C, Meixiong J, Peng Q, Ho CY, et al. MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Sci Transl Med. 2024;16(746):eadk8198.
- Kline SN, Orlando NA, Lee AJ, Wu MJ, Zhang J, Youn C, et al. Staphylococcus aureus proteases trigger eosinophil-mediated skin inflammation. Proc Natl Acad Sci U S A. 2024;121(6):e2309243121.
- Han L, Limjunyawong N, Ru F, Li Z, Hall OJ, Steele H, et al. Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyper-responsiveness. Nat Neurosci. 2018;21(3):324–8.
Curriculum Vitae
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