Academic Position: Assistance Professor
Assist.Prof.Dr.Patimaporn Wongprompitak
Research Profile
Innate immunity and host-pathogen interactions, focusing on infectious disease immunology and cell-based therapeutics are my areas of expertise. My research investigates innate immune responses to tropical pathogens including Burkholderia pseudomallei, Orientia tsutsugamushi, Leptospira, and Pythium insidiosum, with emphasis on Toll-like receptor signaling, inflammasome activation, and antimicrobial peptide production in epithelial and phagocytic cells.
Recent work covers development of cultivated oral mucosal epithelial cells as advanced therapy medicinal products (ATMPs) for limbal stem cell deficiency (LSCD) treatment. The genetic diversity of scrub typhus agents in Southeast Asia has been described by molecular epidemiology investigations.
My research connects basic immunology with clinical applications in infectious diseases, vaccine development, and regenerative medicine.
Publications
- Assantachai P, Niyomnaitham S, Chatthanawaree W, Intalapaporn S, Muangpaisan W, Phannarus H, Saichompoo RB, Sura-Amonrattana U, Wongprompitak P, Toh ZQ, Licciardi PV, Srisutthisamphan K, Chokephaibulkit K. Immunogenicity and reactogenicity of mRNA COVID-19 vaccine booster administered by intradermal or intramuscular route in Thai Older adults. J Infect Dis. 2023: 868-77.
- Inthasin N, Boonwong C, Matamnan S, Sueasuay J, Wongprompitak P, Tanttibhedhyangkul W, Ekpo P. Toll-like receptor 2-mediated induction of human beta-defensin 2 expression by Leptospira interrogans in human kidney cells. Asian Pac J Allergy Immunol. 2023; 41: 389-95.
- Chanmanee T, Ajawatanawong P, Louisirirotchanakul S, Chotiyaputta W, Chainuvati S, Wongprompitak P. Phylogenetic analysis of two new complete genomes of the hepatitis E virus (HEV) genotype 3 from Thailand. Mol Biol Rep. 2020;47(11):8657-68.
- Ekpo P, Inthasin N, Matamnan S, Wongprompitak P, Wattanapanitch M, Boonwong C, Chirapapaisan C, Ngowyutagon P, Uiprasertkul M, Prabhasawat P, Tantibhedhyangkul W. Characterization of limbal explant sites: Optimization of stem cell outgrowth in in vitro culture. PLoS One. 2020; 15(5): e0233075.
- Wongprompitak P, Pleewan N, Tantibhedhyangkul W, Chaiprasert A, Prabhasawat P, Inthasin N, Ekpo P. Involvement of Toll-like receptor 2 on human corneal epithelium during an infection of Pythium insidiosum. Asian Pac J Allergy Immunol. 2020; 38(2): 129-138.
Curriculum Vitae
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