Viral Immunology Research Laboratory

Viral Immunology Research Laboratory

Assoc.Prof.Dr.Kobporn Boonnak
(Ph.D.)

Viral Immunology Research Laboratory explore fundamental aspects of immune responses against important emerging viruses including influenza viruses, Respiratory Syncytial Virus (RSV), Severe Acute Respiratory Virus-2 (SARS-CoV-2), alphaviruses (chikungunya virus), and flaviviruses (dengue and Zika viruses). The goal of our research is to increase basic immunological understanding of these pathogens and their interaction with hosts in order to generate new strategies for preventing and treating viral diseases.

Research Interest

Immunity to respiratory viruses

Immunity to emerging viral diseases of global importance including pandemic human and avian influenza, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Establishment of primary human cells for studying trhe immune responses to respiratory viruses and potential zoonotic viruses
Respiratory virus vaccines

Immunity to arboviruses

Humoral immunity to dengue, Zika and chikungunya viruses
Immune response to zoonotic arboviruses at animal-human interface

Publications

Tongthainan D, Mongkol N, Jiamsomboon K, Suthisawat S, Sanyathitiseree P, Sukmak M, Boonnak K. Seroprevalence of Dengue, Zika, and Chikungunya Viruses in Wild Monkeys in Thailand. Am J Trop Med Hyg. 2020;103(3):1228-33.
Kongchanagul A, Samnuan K, Wirachwong P, Surichan S, Puthavathana P, Pitisuttithum P, Boonnark K. A live attenuated H5N2 prime- inactivated H5N1 boost vaccination induces influenza virus hemagglutinin stalk specific antibody responses, Vaccine. 2020;38(4):852-8.
Boonnak K, Mansanguan C, Schuerch D, Boonyuen U, Lerdsamran H, Jiamsombook K, et al. Molecular Characterization of Seasonal Influenza A and B from Hospitalized Patients in Thailand in 2018-2019. Viruses. 2021;13(6).
Boonnak K, Vogel L, Orandle M, Zimmerman D, Talor E, Subbarao K. Antigen-activated dendritic cells ameliorated influenza A infections. J Clin Invest 2020;130(8):4516.
Boonnak K, Dhitavat J, Thantamnu N, Kosoltanapiwat N, Auayporn M, Jiang L, et al. Immune responses to intradermal and intramuscular inactivated influenza vaccine among older age group. Vaccine. 2017;35(52):7339-46.
Boonnak K, Matsuoka Y, Wang W, Suguitan AL, Jr., Chen Z, Paskel M, et al. Development of Clade-Specific and Broadly Reactive Live Attenuated Influenza Virus Vaccines against Rapidly Evolving H5 Subtype Viruses. J Virol. 2017;91(15).
Pitisuttithum P, Boonnar K, Chamnanchanunt S, Puthavathana P, Luvira V, Lerdsamran H, et al. Safety and immunogenicity of a live attenuated influenza H5 candidate vaccine strain A/17/turkey/Turkey/05/133 H5N2 and its priming effects for potential pre-pandemic use: a randomized, double-blind, placebo-controlled trial. Lancet Infect Dis. 2017;17(8):833-42.

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Viral Immunology Research Laboratory

Viral Immunology Research Laboratory

Department of Immunology

Immunology Graduate Office

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