Pinyadapat Aroonthongsawat, Siriphan Manocheewa, Chatchawan Srisawat , Primana Punnakitikashem , Yaneenart Suwanwong Abstract The goal of this work is to develop a delivery system for histone deacetylase inhibitor (HDACi) romidepsin (ROM) using Poly(D, L-lactide-co-glycolide) as a carrier and evaluate its anti-leukemic effects. Romidepsin-loaded nanoparticles (ROM NPs) required for this purpose were fabricated using a single […]
Category Archives: Research Innovation
Uraiwan Kositanont, Charin Thawornkuno, Athisri Sitthipunya, Worawan Dachavichitlead, Chanwit Tribuddharat, Suppalak Brameld, Galayanee Doungchawee, Benchaporn Lertanantawong, Chatchawan Srisawat Abstract Leptospirosis is a major cause of acute febrile illness, often presenting with non-specific symptoms that can lead to misdiagnosis. Early laboratory diagnosis is essential for confirmation to avoid misdiagnosis and ensure appropriate management. This study aimed […]
Research Innovation
Efficacy, Safety, and Cost-effectiveness of Zinc Oxide Nanoparticles in Whitfield’s Spirit Solution for Treating Superficial Fungal Foot Infections: A Randomized Controlled Trial
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Dec
Dec
Charussri Leeyaphan, Primana Punnakitikashem , Bordeesuda Suiwongsa, Phojana Komesmuneeborirak, Piriyaporn Chongtrakool, Nattanichcha Kulthanachairojana, Pichaya Limphoka, Thrit Hutachoke, Phuwakorn Saengthong-Aram, Pantaree Kobkurkul, Supisara Wongdama, Bawonpak Pongkittilar, Lalita Matthapan, Chatisa Panyawong, Waranyoo Prasong, Akkarapong Plengpanich, Natsuda Kunwong, Kamonlatth Rodponthukwaji, Sumanas Bunyaratavej Abstract Introduction: A novel antifungal formulation combining zinc oxide nanoparticles and Whitfield’s spirit solution (ZnO-WFs) was […]
Kamonlatth Rodponthukwaji, Ladawan Khowawisetsut, Nathachit Limjunyawong, Natsuda Kunwong, Kongpop Duangchan, Sirinapa Sripinitchai, Sith Sathornsumetee, Tam Nguyen, Chatchawan Srisawat, Primana Punnakitikashem Abstract Although the mono-anticancer therapy approach particularly directly targeting tumors is still common, this conventional method is generally deemed not effective and insufficient. In tumor microenvironment (TME), tumor-associated macrophages (TAMs, referred to as M2-polarized) play […]
Kian Hong Kock , Le Min Tan, Kyung Yeon Han, Yoshinari Ando, Damita Jevapatarakul, Ankita Chatterjee, Quy Xiao Xuan Lin, Eliora Violain Buyamin, Radhika Sonthalia, Deepa Rajagopalan, Yoshihiko Tomofuji, Shvetha Sankaran, Mi-So Park, Mai Abe, Juthamard Chantaraamporn, Seiko Furukawa, Supratim Ghosh, Gyo Inoue, Miki Kojima, Tsukasa Kouno, Jinyeong Lim, Keiko Myouzen, Sarintip Nguantad, Jin-Mi Oh, […]
Niken Indrati, Natthaporn Phonsatta, Patcha Poungsombat, Sakda Khoomrung, Atikorn Panya, Punnanee Sumpavapol Abstract Southern Thailand sweet pickled mango (MBC) is a famous delicacy and economically important for the local communities. This study aimed to elucidate important metabolites related to MBC deterioration at 4 °C (STR4) and 30 °C (STR30). The results show that deterioration of […]
Research Innovation
Synergistic anticancer activity of resveratrol-loaded polymeric nanoparticles and sunitinib in colorectal cancer treatment
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Dec
Dec
Punnida Nonsuwan, Nattarika Niwetbowornchai, Kanyanut Insawang, Natsuda Kunwong, Kornrawee Srichan, Chatchawan Srisawat, Paweena Dana, Nattika Saengkrit, Kytai T Nguyen, Primana Punnakitikashem Abstract The development of novel and effective treatment strategies, particularly through drug combinations, can significantly enhance therapeutic outcomes. This study explores the innovative combination of resveratrol (RES), a phenolic compound, with sunitinib (SUNI), a […]
Research Innovation
Comprehensive germline and somatic profiling of high-risk Thai breast cancer via next-generation sequencing
16
Dec
Dec
Kornyok Kamdee, Ekkapong Roothumnong, Wanna Thongnoppakhun, Krittiya Korphaisarn, Panee Nakthong, Peerawat Dungort, Chutima Meesamarnpong, Supakit Wiboontanasarn, Warisara Tansa-Nga, Kittiporn Punuch, Khontawan Pongsuktavorn, Warunya Tititumjariya, Chittapat Lertbussarakam, Jantanee Wattanarangsan, Jiraporn Sritun, Numpueng Ridchuayrod, Manop Pithukpakorn, Bhoom Suktitipat Abstract Breast cancer genomic landscapes differ across ethnic groups, yet the somatic profile of Thai breast tumours has remained […]
Engkarat Kingkaew, Weerapong Woraprayote, Jaruwan Sitdhipol, Ratha-Korn Vilaichone, Wonnop Visessanguan , Somboon Tanasupawat Abstract Probiotics play crucial roles in promoting gut health, enhancing immunity, and combating pathogenic microorganisms, with increasing interest in their applications in the food and therapeutic industries. Lactococcus lactis, a well-known lactic acid bacterium, has emerged as a promising candidate owing to […]
Research Innovation
Performance of electrochemical aptasensor as antigen test in clinical samples for early diagnosis of leptospirosis
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Dec
Dec
Uraiwan Kositanont, Benchaporn Lertanantawong, Kanitha Patarakul, Sirinapa Sripinitchai , Charin Thawornkuno, Thanyarat Chaibun, Chahya Kreangkaiwal, Wassa Waiwinya, Chamras Promptmas, Chatchawan Srisawat Abstract Early diagnosis of leptospirosis is critical for timely treatment and effective disease management. This study evaluated the diagnostic performance of a novel electrochemical aptasensor targeting the electron transfer flavoprotein subunit beta (EtfB) of […]
