Faculty of Medicine Siriraj Hospital, Mahidol University
  • Faculty
    • About Us
      • Our History
      • Vision and Mission
      • Siriraj Culture
      • Awards and Accreditation
      • Facts and Figures
      • Administrative Team
        • Administrative Members
        • Department Chairs
        • Office of the Director
      • Siriraj Booklet 2024
    • Department and Centers
    • Campus Life
      • Accommodation
      • Facilities
      • Virtual Tour
      • Siriraj Museum
  • Program
    • Degree Program
      • International Medical Education (SiIME)
      • BSc in Prosthetics and Orthotics
      • Fellowship and Residency
      • Joint and Dual PhD Program
      • MSc/ PhD Program
    • Training and Exchange
      • Short Training For Healthcare Professional
      • Site Visit
      • Exchange Program
        • International Student
        • Siriraj Medical Student
        • Siriraj Resident/Fellows
    • Scholarship
      • Siriraj Scholarship
        for ASEAN and Developing Countries
  • Research
    • Research Department
      • Research Support
      • Research Highlight
      • Hall of Fame
      • Publication
      • Research Network & Group
    • Siriraj Center of Research Excellence
  • Cooperation
    • MOU Partners
    • Siriraj Visiting Scholars
    • ASEAN Medical School Network
  • Contact Us
  • TH
  • Click to open the search input field Click to open the search input field Search
  • Menu Menu
Left-thin Left-thin Our Highlights

Basivertebral Nerve Ablation (BVNA): A Novel Alternative for Chronic Back Pain Secondary to Vertebral Degeneration

Associate Professor Nantthasorn Zinboonyahgoon, MD
Siriraj Pain Clinic, Department of Anesthesiology
Faculty of Medicine Siriraj Hospital, Mahidol University

Chronic lower back pain remains a critical global public health crisis. Epidemiological data indicate that over 80% of the global population has experienced this condition, with more than 560 million individuals currently enduring chronic pain. This burden severely impacts patients’ quality of life, psychological well-being, and occupational capacity.

While most patients experience improvement through conservative management—such as rest, analgesic medications, or physical therapy—a distinct subset suffers from refractory pain without definitive surgical indications. These patients effectively fall into a “treatment gap,” enduring continuous pain without a targeted therapeutic solution.

🔹 The BVNA Innovation for Vertebrogenic Pain
The Basivertebral Nerve Ablation (BVNA) procedure was developed to specifically address back pain originating from vertebral bone degeneration (vertebrogenic pain). This minimally invasive procedure utilizes high-frequency radio waves (radiofrequency) to ablate the nerve within the vertebral bone tissue, effectively disrupting the nociceptive signaling pathway.
• Safety Profile: This procedure carries a low risk profile and does not require general anesthesia. Medications may be administered to alleviate anxiety and provide analgesia during the procedure. Patients can return home immediately afterward. A potential transient side effect is radiating leg pain (occurring in approximately 10% of cases), which is generally self-limiting.
• Indications: BVNA is indicated for patients with chronic back pain lasting longer than 6 months, accompanied by specific vertebral bone changes detected on MRI at the L3-S1 levels (Modic Changes Type 1-2). However, this procedure is not suitable for individuals with vertebral compression or severe osteoporosis.

🔹 Empirical Evidence
In the United States, this procedure has gained recognition for reimbursement, as studies confirm its cost-effectiveness over long-term treatment with medications and physical therapy. Data demonstrate that a single intervention allows approximately 70% of treated patients to experience sustained clinical improvement for at least 5 to 6 years.

🔹 A Major Milestone for Thailand
For Thailand, on February 5, 2026, the Siriraj Pain Clinic, in collaboration with Seoul National University and led by Dr. Jee Youn Moon, successfully conducted a proctored demonstration and performed the first two BVNA cases in the country. Subsequently, the clinical rollout has expanded across both Siriraj Hospital and Siriraj Piyamaharajkarun Hospital, totaling 4 cases currently.

Based on the precise clinical follow-up of all 4 patients, they reported a pain reduction of more than 50% up to 100%. They have successfully been able to reduce their reliance on analgesic medications, return to their daily activities without pain more effectively, and experienced strictly zero complications from the treatment.

This definitive success elevates Thailand to rank among the first groups of countries in Asia to adopt this technology, alongside South Korea and Indonesia. Although BVNA is not yet covered for reimbursement under current domestic healthcare welfare schemes, it is considered a groundbreaking innovation and beacon of hope that elevates chronic back pain management in Thailand to an equivalent international standard.

Related Highlights

March 5, 2026

Siriraj Faculty Abroad at the 36th American Glaucoma Society Aunnual Meeting in USA

February 18, 2026

Siriraj Faculty Abroad at ISPOR Europe 2025 in UK

February 8, 2026

Siriraj Faculty Abroad at the APAO 2026 in Hong Kong 👁️🔬

February 8, 2026

Siriraj Faculty Abroad at the APAO 2026 in Hong Kong 👁️🔬

February 8, 2026

Siriraj Faculty Abroad at AACA 2026 in Thailand

All Highlights Book-open Book-open

Faculty of Medicine Siriraj Hospital, Mahidol University

2 Wanglang Road Bangkoknoi, Bangkok 10700, Thailand
siiro@mahidol.ac.th

International Office

Site Visit
Siriraj Visiting Scholars
MOU Partners

News

Highlights
Latest News
Newsletter

Study With Us

Exchange Program
Short Training
Siriraj Scholarship

Faculty

Faculty of Medicine Siriraj Hospital

Our Hospital

Siriraj Hospital
Siriraj Piyamaharajkarun Hospital
Golden Jubilee Medical Center

Mahidol Link

Mahidol University

© Copyright - Faculty of Medicine Siriraj Hospital, Mahidol University
Scroll to top Scroll to top Scroll to top