Published Congratulations to Dr. Pattipong Wisanpitayakorn, Dr. Narumol Jariyasopit, and Assoc. Prof. Dr. Sakda Khoomrung of the Siriraj Center of Research Excellence in Metabolomic and Systems Biology (SiCORE-MSB), Faculty of Medicine Siriraj Hospital, Mahidol University, on their latest research publication in the Journal of ACS Measurement Science Au on December 19, 2024. Access the publication via this link:
https://pubs.acs.org/doi/10.1021/acsmeasuresciau.4c00077
This groundbreaking study tackles the challenge of identifying isomeric and isobaric lipids in lipidomics using direct infusion mass spectrometry (DI-MS) and mass spectrometry imaging (MSI) without chromatographic separation. The researchers present a multipass arrival time correction method that works across varying conditions and laboratories, allowing precise annotation of isomeric lipids with a single measurement. This streamlined approach reduces complexity compared to traditional methods. Validation using serum samples demonstrated no matrix effects and minimized drift time differences from over 2% to below 0.2%, irrespective of condition variations.
We celebrate this achievement and its contribution to advancing lipidomics research.
