On April 4–5, 2025, the Center of Research Excellence Management Unit (SiCORE-M) had the great honor of hosting its Annual Seminar: Retreat 2025 at the Howard Johnson by Wyndham Pattaya JC Hotel, Chonburi Province. The event was presided over by Professor Apichat Asavamongkolkul, M.D., Dean of the Faculty of Medicine Siriraj Hospital, who served as […]
On January 21, 2025, the executive team from the Faculty of Medicine Siriraj Hospital, led by Dean Professor Apichat Asavamongkolkul, along with Deputy Dean for Research and Innovation, Assoc. Prof. Sith Sathornsumetee, Head of the Center of Research Excellence (SiCORE-M), and Assistant Professor Woraphat Ratta-Apha visited the SiCORE-DO center at the SiMR Building. The SiCORE-DO team warmly welcomed the executive team, represented by Prof.Nattachet Plengvidhya, the Director, and his SiCORE-DO team members.
During the visit, the SiCORE-DO team presented key achievements and an operational progress report, highlighting advancements in diabetes and obesity research. The session fostered valuable discussions on strategic initiatives and future directions, reinforcing our unwavering commitment to driving impactful research and innovation in metabolic diseases. This commitment is a beacon of inspiration, guiding our collective efforts toward a healthier future.
We are thrilled to announce that our latest research on enhancing the immune system’s ability to combat cholangiocarcinoma (bile duct cancer) has been accepted for publication in Biomedicine & Pharmacotherapy (Impact Factor: 6.9)! 🎉
Led by researchers at the Siriraj Center of Research Excellence for Systems Pharmacology (SiSP) in collaboration with expert partners, this study uncovers a promising strategy to restore immune function in this highly aggressive cancer. By reactivating the body’s natural defenses, this approach brings new hope for more effective treatments.
🔬 Read the full research highlight here: https://www.sisyspharm.org/highlights/reactivating-the-bodys-natural-defenders-a-new-hope-for-fighting-cholangiocarcinoma
Every day, billions of cells in our body divide, grow and repair tissue, ensuring our health and survival. This process, known as the cell cycle, is tightly regulated to prevent errors. When these controls fail, diseases like cancer—where cells divide uncontrollably—can arise.
At the heart of this regulation is FOXM1, a crucial protein that acts as a conductor, directing cells through different stages of the cycle. While FOXM1’s role in normal cell growth is well established, its behavior in individual cells—especially under conditions of disruption—has remained a mystery.
Our latest study uncovers how FOXM1 responds to different cellular conditions, offering new insights into its role in cancer development and potential therapeutic strategies. Understanding this mechanism brings us one step closer to more precise cancer treatments.
🔬 Read the full research highlight here: https://www.sisyspharm.org/highlights/decoding-the-cell-cycle-how-a-key-protein-shapes-cell-fate-and-cancer-treatment
Kamonlatth Rodponthukwaji, PhD, a researcher from the Research Department at Siriraj Hospital, Faculty of Medicine, Mahidol University, attended and presented a poster at the 8th International Conference on Multifunctional, Hybrid and Nanomaterials held in Montpellier, France, from March 3rd to 6th, 2025. Dr. Rodponthukwaji presented a poster titled “Development of a targeted dual-ligand liposomal system to improve therapeutic efficacy against mutant glioblastoma”.
Dr. Rodponthukwaji’s participation will benefit Siriraj Hospital by fostering research collaborations, increasing academic recognition, and advancing nanomedicine applications. Through engagement with leading experts and institutions, the hospital can establish new partnerships for joint research, secure funding opportunities, and facilitate technology transfer. The insights gained from the conference can drive innovation in diagnostics, drug delivery, and biomaterials, ultimately contributing to improved patient care.
